11 Most Helpful Supplements for Hashimoto's
- Poppy Road
- Oct 6
- 4 min read

Living with Hashimoto's Thyroiditis means navigating an autoimmune condition where your immune system attacks your thyroid gland. While medication is a cornerstone of treatment, many people find that targeted nutritional support can make a significant difference in managing symptoms and improving overall quality of life. The right supplements can help reduce inflammation, support thyroid function, and address common related issues like gut health and fatigue.
This guide explores some of the most helpful supplements for Hashimoto's, offering insights into how they can support your journey toward better health. We will cover how certain supplements can help reduce thyroid antibodies, improve gut function, and boost your energy levels.
Understanding the Role of Supplements in Hashimoto's
Supplements are not a replacement for prescribed thyroid medication, but they can be a powerful complement to your treatment plan. They work by addressing underlying imbalances that often accompany autoimmune conditions. For instance, many people with Hashimoto's experience nutrient deficiencies, poor gut health, and adrenal fatigue.
By strategically incorporating supplements, you can provide your body with the tools it needs to function more optimally. This approach to autoimmune support can help you manage symptoms like fatigue, anxiety, and joint pain.
Key Supplements for Thyroid Health
Here are some of the most effective supplements that have shown promise for individuals with Hashimoto's.
1. Naltrexone (Low Dose Naltrexone - LDN)
While technically a medication used in an off-label capacity, Low Dose Naltrexone (LDN) deserves a spot on this list due to its remarkable impact on autoimmune conditions. LDN is thought to work by briefly blocking opioid receptors, which in turn signals the body to increase its production of endorphins. This boost can help regulate the immune system, leading many to see excellent results in reducing thyroid antibodies.
2. Probiotics
A healthy gut is foundational to a healthy immune system. Since Hashimoto's is an autoimmune disease, supporting your gut microbiome is crucial. Probiotics introduce beneficial bacteria that help restore balance, improve digestion, and strengthen the gut lining. Furthermore, research suggests over 50% of Hashimoto's patients also have Small Intestinal Bacterial Overgrowth (SIBO). Certain probiotic strains can help address SIBO and alleviate related symptoms like bloating and anxiety.
3. Selenium
Selenium is a true powerhouse for thyroid health. This essential mineral is a key component of the enzymes that convert the inactive thyroid hormone (T4) into the active form (T3). Supplementing with selenium has been shown to reduce thyroid peroxidase (TPO) antibodies, which are a marker of the autoimmune attack on the thyroid. By lowering these antibodies, selenium can help protect thyroid tissue from damage and ease symptoms like anxiety.
4. Betaine with Pepsin
Many individuals with Hashimoto's have low stomach acid, a condition that impairs protein digestion and nutrient absorption. This can lead to significant fatigue and other deficiencies. Betaine with Pepsin is a supplement that supports healthy stomach acid levels, ensuring you can properly break down food and absorb vital nutrients. For many, restoring proper digestion is a turning point in overcoming debilitating fatigue.
5. Systemic Enzymes
Systemic enzymes work throughout the body to break down inflammatory proteins and immune complexes. For those with Hashimoto's, this can be incredibly beneficial for reducing thyroid antibodies and calming the immune response. Many people also find that systemic enzymes help reduce food sensitivities, a common issue with autoimmune diseases. This can lead to a reduction in related symptoms like joint pain, skin breakouts, and stomach pain.
6. Moducare
Moducare is a specialized blend of plant sterols and sterolins that helps balance and regulate the immune system. It's an immunomodulator, meaning it doesn't suppress or boost the immune system but helps it function more intelligently. This supplement can be a dream team for both adrenal and immune support, helping to reduce thyroid antibodies and improve adrenal function, which is often stressed in chronic illness.
7. Thiamine (Vitamin B1)
Known as the "fatigue terminator," Thiamine plays a critical role in energy metabolism. It's also essential for the production of hydrochloric acid in the stomach, tying back to the importance of healthy digestion. Since low stomach acid is common in Hashimoto's, ensuring adequate Thiamine levels can support proper nutrient absorption. Additionally, this vital B vitamin supports adrenal function and helps stabilize blood sugar, further contributing to improved energy levels.
8. Vitamin D
Often called the "sunshine vitamin," Vitamin D acts more like a hormone in the body and plays a huge role in modulating the immune system. Studies have consistently shown a link between Vitamin D deficiency and an increased risk of autoimmune diseases, including Hashimoto's. Supplementing can help regulate your immune response and may lower thyroid antibody levels.
9. Magnesium
Magnesium is involved in over 300 biochemical reactions in the body, including the conversion of T4 to T3. Many people with Hashimoto's are deficient in this crucial mineral. Supplementing with magnesium can help with common symptoms like fatigue, muscle cramps, anxiety, and constipation. It also plays a role in blood sugar regulation and adrenal health.
10. Zinc
Zinc is another mineral that is vital for thyroid hormone production. It helps the hypothalamus regulate the release of thyroid-stimulating hormone (TSH). A deficiency in zinc can lead to impaired thyroid function. This mineral also has important immune-modulating properties and is essential for maintaining a healthy gut lining.
11. B-Complex Vitamins
Beyond just Thiamine (B1), the entire family of B vitamins is crucial for energy production, adrenal support, and neurological function. Vitamins like B12 and folate are particularly important for fighting fatigue and brain fog, two of the most common complaints among those with Hashimoto's. A high-quality B-complex supplement ensures you are getting a balanced blend to support your overall well-being.
Your Next Steps with Citrus Telemedicine
Navigating Hashimoto's requires a comprehensive approach, and integrating the right supplements can be a key part of your wellness strategy. However, it's essential to work with a healthcare professional who understands the complexities of autoimmune thyroid disease.
At Citrus Telemedicine, we provide personalized care to help you manage your Hashimoto's. Our team can help you identify nutrient deficiencies through testing and create a targeted supplement plan that is safe and effective for your unique needs.
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